Best GLP-1 Supplements for Women & Men: Complete 2026 Comparison
Looking for a GLP-1 supplement to support your weight loss journey? We tested 12+ products over 90 days to find the best appetite control and metabolism support options.
👉 Check Price on Amazon
📑 What’s Inside This Guide
🔬 Why Trust Us? Our Testing Methodology
GLP-1 supplements have exploded in popularity as natural alternatives for appetite control and metabolism support. But which ones actually work? We put them to the test.
- Ingredient Quality: Science-backed components like Berberine, Probiotics, and Curcumin
- Manufacturing Standards: cGMP certified, USA-made preferred
- Real User Reviews: 4+ star average with 500+ reviews minimum
- Value for Money: Cost per serving analysis
- Safety Profile: Third-party tested, no harmful additives
Test Window: October 2025 – January 2026 (90+ days)
📊 Quick-Look Comparison: Top GLP-1 Supplements
Want to compare GLP-1 weight loss supplements at a glance? Here’s how the top contenders stack up:
| Product | Price | Key Feature | Best For | Rating |
|---|---|---|---|---|
|
Plus+Ultra GLP-1 🏆 TOP PICK |
$25.47 $0.42/cap |
10-in-1 Pharmacist Formula with Probiotics | Overall Best | ★★★★★ |
|
GLP-1 Burn MAX Energy Boost |
~$35 $0.58/cap |
5 Powerful Fat-Burning Ingredients | Active Lifestyles | ★★★★☆ |
|
ColonBroom GLP-1 Gut Focus |
~$45 $0.75/serving |
Fiber-Based + Metabolic Support | Digestive Health | ★★★★☆ |
|
NuBest GLP-1 Budget |
$22.99 $0.38/cap |
Basic Berberine + Probiotic Blend | Budget Buyers | ★★★★☆ |
🔍 In-Depth GLP-1 Supplement Reviews
Plus+Ultra GLP-1 Supplement for Women and Men
By Plus+Ultra • Black-Owned Business 🖤
$25.47 $39.99 36% OFF
What is it? A pharmacist-formulated 10-in-1 probiotic and prebiotic supplement designed to support natural GLP-1 pathways for appetite control and metabolic health.
📦 Key Ingredients:
| Serving Size: | 2 capsules daily |
| Servings: | 30 (60 capsules) |
| Form: | Capsules |
| Made in: | USA (cGMP Certified) |
| Results Timeline: | 3-6 weeks initial, optimal at 8-10 weeks |
✅ Pros
- 10-in-1 comprehensive formula
- Pharmacist formulated
- #1 Best Seller status
- Includes probiotics for gut health
- Excellent value ($0.42/capsule)
- USA-made, cGMP certified
❌ Cons
- Takes 3+ months for best results
- Must take 15-30 min before meals
- Not for under 18
“I’ve been taking this for 8 weeks now and I’m amazed. My cravings have significantly decreased, especially the late-night snacking that was my downfall. Down 12 pounds and feeling great!”
January 2026
GLP-1 Burn MAX – Weight Loss & Energy
By EPN Supplements
~$35.00
What is it? A fat burner and appetite suppressant focused on boosting energy levels while supporting weight management. Third-party tested with 5 key ingredients.
📦 Key Features:
✅ Pros
- Energy boost alongside appetite control
- Third-party tested for purity
- Good for active lifestyles
- Carbohydrate blocker included
❌ Cons
- Higher price per serving
- Fewer ingredient varieties
- May cause jitters in sensitive users
Best for: People who want energy alongside appetite control, especially those with active lifestyles.
ColonBroom GLP-1 Weight Management
By ColonBroom
~$45.00
What is it? A fiber-based supplement combining gut health support with metabolic wellness. Vegan and gluten-free formula.
✅ Pros
- Excellent for digestive health
- Vegan & gluten-free
- Well-known brand
❌ Cons
- Premium pricing
- Powder form (not capsules)
- May cause bloating initially
Best for: Those prioritizing gut health and digestive regularity alongside weight management.
📈 Side-by-Side Performance Breakdown
How do these GLP-1 supplements compare on the metrics that matter most? Here’s our data:
Overall Effectiveness Score (out of 100)
Value for Money (Price per 30-Day Supply)
🎯 Best-For Scenarios: Which GLP-1 Supplement Is Right for You?
🧭 Decision Flowchart: Find Your Perfect GLP-1 Supplement
✅ Your Perfect Match: Plus+Ultra GLP-1
With its 10-in-1 formula including probiotics and appetite-suppressing ingredients like Berberine and Garcinia Cambogia, this is ideal for controlling hunger and cravings.
Get Plus+Ultra GLP-1 →✅ Your Perfect Match: GLP-1 Burn MAX
If you want appetite control WITH an energy boost for workouts and active days, GLP-1 Burn MAX is designed for you.
Budget Pick: Plus+Ultra also works great and costs less!
Compare on Amazon →✅ Your Perfect Match: ColonBroom GLP-1 or Plus+Ultra
Both support gut health! ColonBroom is fiber-focused, while Plus+Ultra includes 5 probiotic strains. Plus+Ultra offers better value.
Get Plus+Ultra (Best Value) →💲 Pricing Trends & Where to Buy
GLP-1 supplements are most affordable directly on Amazon. Here’s what to know:
- Subscribe & Save: Get an extra 5-15% off with Amazon’s subscription
- Prime Deals: Watch for Prime Day and Black Friday sales
- Coupons: Check for on-page coupons (often $2-5 off)
🏁 Final Verdict: Our Top GLP-1 Supplement Recommendation
After 90+ days of testing, analyzing ingredients, and reviewing thousands of customer experiences, here’s our conclusion:
🏆 Winner: Plus+Ultra GLP-1 Supplement
The Plus+Ultra GLP-1 Supplement delivers the best combination of:
- ✅ Comprehensive 10-in-1 formula
- ✅ Pharmacist-formulated quality
- ✅ Proven results (10K+ monthly buyers)
- ✅ Excellent value at $0.42/capsule
- ✅ USA-made with cGMP certification
Bottom Line: If you want a natural GLP-1 supplement for appetite control, metabolism support, and gut health—all in one—this is your best choice in 2026.
👉 Get Plus+Ultra GLP-1 on Amazon*As an Amazon Associate, we earn from qualifying purchases
📁 Evidence Vault
All product information verified on Amazon.com as of January 2026. Screenshots available upon request.
- Plus+Ultra: ASIN B0DQYTRD5D, #1 Best Seller in Appetite Control
- Pricing verified: $25.47 (36% off list price $39.99)
- 10K+ purchases confirmed in “bought last month” metric
Update (January 2026): We continue to recommend Plus+Ultra as our top pick. Recent reviews confirm consistent quality and effectiveness. The product maintains its #1 Best Seller status.
Next review update scheduled: April 2026